FUNCTIONING OF CARBOXYTHERAPY
ALL YOU NEED TO KNOW ABOUT THE TECHNIQUE
WHAT IS CARBOXYTHERAPY
The term "carboxytherapy" itself means the use of carbon dioxide (CO2) for therapeutic purposes. Nowadays, the same term mean:
- The use of CO2 transcutaneously, by external contact with the skin
La prima accezione nasce nel 1930 in Francia presso la stazione termale di Royat dove nel trattamento di pazienti affetti da arteriopatie periferiche, è stata utilizzata CO2 per via transcutanea attraverso docce filiformi e bagni carbo-gassosi secchi o in acqua carbonica.
Per molti anni è stata effettuata solo in istituti termali perché questo trattamento necessitava di specifiche attrezzature per lo smaltimento del gas (CO2).
Gli effetti benefici a livello microcircolatorio hanno permesso un utilizzo di questo trattamento come supporto alle terapie convenzionali nelle arteriopatie periferiche, nelle flebolinfopatie, nelle acrocianosi e nelle lesioni ulcerative di diversa genesi, migliorando il trofismo dei tessuti e permettendo una migliore granulazione del fondo ulcerativo.
FROM THERMAL BATHS...
- the administration of CO2 by subcutaneous injections, controlled by a patented device.
L’efficacia di questa terapia in campo termale spinge il nostro CEO Roberto Parmigiani a pensare che la CO2 potesse essere efficace anche somministrata per via intradermica. Da questo impulso parte lo sviluppo di un device che potesse controllare il flusso di gas che viene realmente iniettato sottocute, la variabile più importante per ottenere dei risultati scientificamente rilevanti.
Il primo device l’abbiamo chiamato Carbomed e l’abbiamo brevettato perchè è stato grazie a questa apparecchiatura che si è potuta dimostrare l’efficacia della Carbossiterapia per via invasiva in diversi ambiti di applicazione: vengono pubblicati numerosi studi scientifici in riviste accreditate e il termine “CARBOXYTHERAPY” inizia a diffondersi nel senso di “somministrazione sottocutanea di CO2 controllata da un device brevettato”.
Questa accezione è quella oggi più diffusa ed è ormai entrata nel bagaglio e nella pratica clinica in diversi ambiti della medicina funzionale ed estetica.
MECHANISM OF ACTION AND EFFECTS
The CO2 flow breaks the membranes of fat cells as a direct lipoclasic action, keeping vessels and connective tissue without any damage.
– The increased supply and release of oxygen at tissues’ level promotes oxidative processes of fatty acids (enzymes able to dissolve fats)
– The increase of local blood flow reactivates cellular metabolism, triggering a greater energy demand by adipose tissue and therefore stimulating lipolysis process.
The speed of elimination of liquid stagnation increases, as much to obtain primary lymphatic drainage even in the most severe cases (e.g. severe lymphedema)
– By inducing vasodilation and improving the pumping action on the blood by the arterioles, it causes an increase in the speed of the local tissue blood flow.
– Causes an increase in the release of oxygen at the tissue level (Bohr effect)
– Induces a mediated angiogenesis by the release of growth factors.
The mechanism by which the administration of CO2 can determine the analgesic effect is not yet known. Some authors suggest that it be achieved thanks to:
– Direct action with the inhibition of trigger points
– Relaxing of muscle fiber cells of the precapillary sphincters (due to the increase of blood flow) whose receptors, once they are stimulated, have a feedback action on the central nervous system
– Secondary inhibitory influences on the cytokines
The hyperinflation of subcutaneous tissues generated by the flow, stimulates metabolism of fibroblasts, which will produce more hyaluronic acid, collagen and elastic fibers: all these factors contribute to the improvement of skin tone and elasticity.
The oxygenation of skin cells stimulates them to reproduce themselves faster, changing the texture of the skin and giving it a brighter appearance.
CARBOXYTHERAPY is NOT simply a subcutaneous administration of carbon dioxide in gaseous form, but a method whose safety and efficacy are guaranteed by multiple factors
Although the treatment is non-invasive and does not require any type of anesthesia, it must always be performed by a doctor, to ensure correct diagnosis with his professionalism, the attention paid in the choice of equipment, in the choice of the protocol to be used and in the its customization.
It is necessary to constantly monitor and control the real flow of gas within the tissues.
The doctor will have to follow specific and previously scientifically tested treatment protocols.
DURING THE SESSION
It can be felt when the gas tries to "make its way" in the subcutaneous, a slightly annoying sensation that decreases significantly after the first 2-5 minutes and which disappears completely within the first hour of treatment
They are very rare, equal to 5% of current cases, which disappear in a few days.
This data, initially present in 70% of patients, has now partially disappeared with the introduction of the CDT Evolution device and new treatment protocols.
In any case, we invite the patient to communicate any kind of discomfort during the treatment to the doctor, so that he can modify the administration parameters thus adapting the method in order to make it as comfortable as possible.
WHEN AND HOW MUCH
The duration of a session varies from 10 to 30 minutes depending on the pathology to be treated.
A cycle varies from 8 to 15 sessions based on the pathology to be treated, usually once or twice a week, on the advice of the doctor.
Being the developers of the method, we cannot give precise indications about the cost of a session. We know that those who work with our devices in Italy offer treatment at a variable cost of 80-120 euros per session. Costs may vary depending on the integrated protocols (therapeutic package).
WHY IS SAFE
IT IS A GAS, BUT IT DOES NOT CAUSE EMBOLISM
Carbon dioxide is composed by one carbon atom linked to two oxygen atoms (CO2). (picture of CO2 molecule)
Every day our body produces around 450 liters of CO2 (from 200mL/min to 2L/min) as an effect of “cellular respiration”, thanks to a series of chemical reactions in presence of oxygen that allows to burn sugars producing energy.
About 70% of CO2 molecules that enter in the blood are transported to the lungs through bicarbonate ions dissolved in the plasma. This process allows to maintain the stability of body pH and, at the same time, to exchange CO2 with oxygen in the lung alveoli and then expel it with exhalation.
SPARKLING? NO, THERAPEUTIC!
For this reason CO2 is non-toxic: it is physiologically eliminated through the lungs.
We commonly think in CO2 in terms of sparkling water bubbles. However, in medicine field it has long been widely used. As it is an inert gas and directly produced by our body, it has been possible to use it in different techniques, such as in laparoscopic surgery and in colonoscopy exams.
To be used in the medical field, carbon dioxide must be produced by specialized companies that make it bacteriologically pure, guaranteeing its sterility: this is why we speak about medical CO2, non-toxic.
WHAT IT MEANS TO HAVE A PATENT …
Therapeutic efficacy strictly depends on the possibility of controlling the gas flow within the tissue, therefore it is clear that the choice of the type of equipment to be used makes the difference.
We have patented this possibility: the software of our medical devices is patented for the control of subcutaneous and intradermal impedances, modulating the administration in real time throughout the treatment according to the degree of laxity or compactness of the tissue.
BEYOND THE CYLINDER
In addition to gas, it is important that the entire infusion system is in sterile conditions: first of all a series of anti-pore filters purify the CO2 of possible contaminants, subsequently our devices constantly verify the purity of the gas and finally the micro-injections are carried out through a kit composed by a dispensing tube equipped with a very thin needle (30G of 13mm) in sterile disposable package, to avoid the risk of hemo-transmissible diseases.